Choose this medication by mouth with or without food with a complete glass of water (eight ounces or 240 milliliters) or as directed by your medical professional. This medication may very well be taken with foods or milk if belly upset takes place. The dosage is predicated in your health-related problem and reaction to procedure.
Drug interactions, including a heightened incidence of extrapyramidal results, happen to be claimed when some MAOI and phenothiazines are applied concomitantly.
In animal reproduction scientific tests, codeine administered by the oral route to pregnant rats in the period of organogenesis increased resorptions and lowered fetal weights in a dose roughly 25 occasions the maximum advised human dose (MRHD) from the presence of maternal toxicity (see Knowledge).
Minimal Hypertension (Hypotension). Promethazine/codeine could trigger small blood pressure. If you feel faint or dizzy, lie down. Notify your healthcare company immediately When you have any of the following signs of very low blood pressure level.
Affected person security is our top priority. Codeine linctus is a highly effective medicine for long-lasting dry cough, but as it's an opioid, its misuse and abuse can have major health implications.
If you really feel you are addicted or have worries for someone who has actually been applying codeine linctus for too extended, you could seek out suggestions within the NHS Web page. Support groups and self-aid teams also are available which include Check with FRANK.
Hemodialysis is not routinely used to improve the elimination of codeine more info or promethazine from your body.
The specific mechanism of motion of codeine as well as other opiates is not really known; having said that, codeine is believed to act centrally about the cough Heart. In excessive doses, codeine will depress respiration.
This products could lead to critical mental/temper adjustments and very really serious (almost never lethal) respiratory troubles. This merchandise could include codeine or dihydrocodeine. Codeine and dihydrocodeine are adjusted into sturdy opioid prescription drugs (morphine or dihydromorphine) in Your entire body.
Treatment method: The remedy of overdosage with promethazine and codeine is essentially symptomatic and supportive. Only in situations of extreme overdosage or individual sensitivity do click here crucial signals including respiration, pulse, blood pressure level, temperature, and EKG have to be monitored. Activated charcoal orally or by lavage may be given, or sodium or magnesium sulfate orally to be a cathartic. Consideration needs to be provided towards the reestablishment of ample respiratory exchange by provision of a patent airway and institution of assisted or controlled air flow.
Although the chance of dependancy in any specific is unfamiliar, it could manifest in sufferers appropriately prescribed Promethazine HCl and Codeine Phosphate Oral Option. Addiction can manifest at advised dosages and if the drug is misused here or abused. Challenges are improved in people with a personal or relatives background of material abuse (including drug or Liquor abuse or dependancy) or mental disease (e.g., major melancholy).
Normally examine the label and only use as directed. Should you be Doubtful, speak to a Health care professional.
Codeine Codeine is really an opioid agonist more info relatively selective to the mu-opioid receptor, but with a much weaker affinity than morphine. The analgesic and antitussive properties of codeine are speculated to come from its conversion to morphine.
This medicine may possibly consist of aspartame. When you've got phenylketonuria (PKU) or some other ailment that requires you to limit your ingestion of check here aspartame (or phenylalanine), speak to your medical professional or pharmacist regarding the safe use of this medication.